Scientists OBNARUZHILI discovers the sleep disorders with one of the spread of disease

Violation of the daily rhythm, might contribute to the development of type 2 diabetes among those who receive a particular gene.

Accommodation at night and watch the day – not just a matter of habit. At various times of day in the body are different processes, different biochemical reactions that are not reviewed until the end. But it is well known that violations of the daily rhythm affect health.

Another proof of this is a large international team of scientists, among whom there are few Russians working abroad. Their article published the current issue Nature Genetics. They found that a particular gene variant, which is responsible for developing a protein that could be sensitive to the hormone melatonin, increases the risk of type 2 diabetes, or age, as it is also called.

Melatonin, which produces a thymus – a small pineal gland, is governed mainly subsistence and other rhythms in the body. As he relates, and the growth of blood sugar, it is not yet clear. The hypothesis that brought scientists, is as follows. Receptors in our eyes and brain react to the light and transmit the signal to reduce the formulation of sleep hormone melatonin thymus. Information comes in the pancreas that produce insulin to glucose assimilation. If the gene, to manage these processes, there has been a mutation, those relationships are violated, the insulin produced is not enough – blood sugar levels may rise. For the pilot study, scientists hope to simulate the gene mutation in mice.

In the meantime, they analyzed the data of thousands of patients and found that the modified gene increases the risk of developing diabetes. If the parents inherited one copy of this gene, at 9%, if just two – that almost 20%. And among those who have disrupted sleep, or who have long worked at night, type 2 diabetes occurs much more frequently. An increasing blood sugar level and when Diabetics taking pills of synthetic melatonin, which often advise doctors to overcome the syndrome of the change time zones to travel far or as mild narcotic.